TORTINI

For your delectation and delight, desultory dicta on the law of delicts.

Slide Rule 702

June 26th, 2021

Note: A “fatal error,” caused by an old theme has disrupted the layout of my website. I am working on it

The opposition to Daubert’s regime of gatekeeping by the lawsuit industry has been fierce. From the beginning, the resistance has found allies on the bench, who have made the application of Rule 702 to expert witnesses, in both civil and criminal, uneven at best. Back in 2015, Professor David Bernstein and Eric Lasker wrote an exposé, about the unlawful disregard of the statutory language of Rule 702, and they called for and proposed an amendment to the rule.[1] At the time, I was skeptical of unleashing a change through the rules committee, given the uncertainty of where any amendment might ultimately look like.[2]

In the last several years, there have been some notable applications of Rule 702 in litigation involving sertraline, atorvastatin, sildenafil, and other medications, but aberrant decisions have continued to upend the rule of law in the area of expert witness gatekeeping. Last year, I noted that I had come to see the wisdom of Professor Bernstein’s proposal,[3] in the light of continued judicial dodging of Rule 702.[4] Numerous lawyers and legal organizations have chimed in to urge a revision to Rule 702.[5]

Earlier this week, the Committee on Rules of Practice & Procedure rolled out a proposed draft of an amended Rule 702.[6] The proposed new rule looks very much like the current rule:[7]

  1. Rule Testimony by Expert Witnesses
  2. A witness   who   is   qualified   as   an   expert   by
  3. knowledge, skill,  experience,  training,  or  education may
  4. testify in the form of an opinion or otherwise if the proponent
  5. has demonstrated by a preponderance of the evidence that:
  6. (a) the  expert’s  scientific,  technical,  or  other
  7. specialized knowledge will help the trier of
  8. fact  to   understand   the   evidence   or   to
  9. determine a fact in issue;
  10. (b) the testimony is based on sufficient facts or
  11. data;
  12. (c) the  testimony  is  the  product  of  reliable
  13. principles and methods; and
  14. (d) the  expert  has  reliably  applied  expert’s
  15. opinion reflects a reliable application of the
  16. principles and methods to the facts of the
  17. case

Despite what looks like minor linguistic changes, the Rules Committee’s note suggests otherwise. First, the amendment is intended to emphasize that the burden of showing the admissibility requirements rests on the proponent of the challenged expert witness testimony. Of course, the burden of course has always been with the proponent, but some courts have deployed various strategems to shift the burden with conclusory assessments that the challenge “goes to the weight not the admissibility,” thereby dodging the judicial responsibility for gatekeeping. The Committee now would make clear that many courts have erred by having treated the “critical questions of the sufficiency of an expert’s basis, and the application of the expert’s methodology” as going to weight and not admissibility.[8]

The Committee appears, however, to be struggling to provide guidance on when challenges do raise “matters of weight rather than admissibility.” For instance, the Committee Note suggests that:

“nothing in the amendment requires the court to nitpick an expert’s opinion in order to reach a perfect expression of what the basis and methodology can support. The Rule 104(a) standard does not require perfection. On the other hand, it does not permit the expert to make extravagant claims that are unsupported by the expert’s basis and methodology.”[9]

Somehow, I fear that the mantra of “weight not admissibility” has been or will be replaced by refusals to nitpick an expert’s opinion. How many nits does it take to make a causal claim “extravant”?

Perhaps I am the one nitpicking now. The Committee has recognized the essential weakness of gatekeeping as frequently practiced in federal courts by emphasizing that judicial gatekeeping is “essential” and required by the institutional incompetence of jurors to determine whether expert witnesses have reliably applied sound methodology to the facts of the case:

“a trial judge must exercise gatekeeping authority with respect to the opinion ultimately expressed by a testifying expert. A testifying expert’s opinion must stay within the bounds of what can be concluded by a reliable application of the expert’s basis and methodology. Judicial gatekeeping is essential because just as jurors may be unable to evaluate meaningfully the reliability of scientific and other methods underlying expert opinion, jurors may also be unable to assess the conclusions of an expert that go beyond what the expert’s basis and methodology may reliably support.”[10]

If the sentiment of the Rule Committee’s draft note carries through to the Committee Note that accompanies the amended rule, then perhaps some good will come of this effort.


[1] David E. Bernstein & Eric G. Lasker,“Defending Daubert: It’s Time to Amend Federal Rule of Evidence 702,” 57 William & Mary L. Rev. 1 (2015).

[2]On Amending Rule 702 of the Federal Rules of Evidence” (Oct. 17, 2015).

[3]Should Federal Rule of Evidence 702 Be Amended?” (May 8, 2020).

[4]Dodgy Data Duck Daubert Decisions” (April 2, 2020); “Judicial Dodgers – The Crossexamination Excuse for Denying Rule 702 Motions” (May 11, 2020); “Judicial Dodgers – Reassigning the Burden of Proof on Rule 702” (May 13, 2020); “Judicial Dodgers – Weight not Admissibility” (May 28, 2020); “Judicial Dodgers – Rule 702 Tie Does Not Go to Proponent” (June 2, 2020).

[5] See, e.g., Daniel Higginbotham, “The Proposed Amendment to Federal Rule of

Evidence 702 – Will it Work?” IADC Products Liability Newsletter (March 2021); Cary Silverman, “Fact or Fiction: Ensuring the Integrity of Expert Testimony,” U.S. Chamber Instit. Leg. Reform (Feb. 2021); Thomas D. Schroeder, “Federal Courts, Practice & Procedure: Toward a More Apparent Approach to Considering the Admission of Expert Testimony,” 95 Notre Dame L. Rev. 2039, 2043 (2020); Lee Mickus, “Gatekeeping Reorientation: Amend Rule 702 To Correct Judicial Misunderstanding about Expert Evidence,” Wash. Leg. Foundation (May 2020)

13-18 (noting numerous cases that fail to honor the spirit and language of Rule 702); Lawyers for Civil Justice, “Comment to the Advisory Comm. on Evidence Rules and its Rule 702 Subcommittee; A Note about the Note: Specific Rejection of Errant Case Law is Necessary for the Success of an Amendment Clarifying Rule 702’s Admissibility Requirements 1 (Feb. 8, 2021) (arguing that “[t]he only unambiguous way for the Note to convey the intent of the amendment is to reject the specific offending caselaw by name.”).

[6] Committee on Rules of Practice & Procedure Agenda Book (June 22, 2021). See Email Cara Salvatore, “Court Rules Committee Moves to Stiffen Expert Standard,” Law360 (June 23, 2021).

[7] Id. at 836. The proposal has been the subject of submissions and debate for a while. See Jim Beck, “Civil Rules Committee Proposes to Toughen Rule 702,” Drug & Device Law (May 4, 2021).

[8] Committee on Rules of Practice & Procedure Agenda Book at 839 (June 22, 2021).

[9] Id.

[10] Id. at 838-39.

A Proclamation from the Task Force on Statistical Significance

June 21st, 2021

The American Statistical Association (ASA) has finally spoken up about statistical significance testing.[1] Sort of.

Back in February of this year, I wrote about the simmering controversy over statistical significance at the ASA.[2] Back in 2016, the ASA issued its guidance paper on p-values and statistical significance, which sought to correct misinterpretations and misrepresentations of “statistical significance.”[3] Lawsuit industry lawyers seized upon the ASA statement to proclaim a new freedom from having to exclude random error.[4] To obtain their ends, however, the plaintiffs’ bar had to distort the ASA guidance in statistically significant ways.

To add to the confusion, in 2019, the ASA Executive Director published an editorial that called for an end to statistical significance testing.[5] Because the editorial lacked disclaimers about whether or not it represented official ASA positions, scientists, statisticians, and lawyers on all sides were fooled into thinking the ASA had gone whole hog.[6] Then ASA President Karen Kafadar stepped into the breach to explain that the Executive Director was not speaking for the ASA.[7]

In November 2019, members of the ASA board of directors (BOD) approved a motion to create a “Task Force on Statistical Significance and Replicability.”[8] Its charge was

“to develop thoughtful principles and practices that the ASA can endorse and share with scientists and journal editors. The task force will be appointed by the ASA President with advice and participation from the ASA BOD. The task force will report to the ASA BOD by November 2020.

The members of the Task Force identified in the motion were:

Linda Young (Nat’l Agricultural Statistics Service & Univ. of Florida; Co-Chair)

Xuming He (Univ. Michigan; Co-Chair)

Yoav Benjamini (Tel Aviv Univ.)

Dick De Veaux (Williams College; ASA Vice President)

Bradley Efron (Stanford Univ.)

Scott Evans (George Washington Univ.; ASA Publications Representative)

Mark Glickman (Harvard Univ.; ASA Section Representative)

Barry Graubard (Nat’l Cancer Instit.)

Xiao-Li Meng (Harvard Univ.)

Vijay Nair (Wells Fargo & Univ. Michigan)

Nancy Reid (Univ. Toronto)

Stephen Stigler (Univ. Chicago)

Stephen Vardeman (Iowa State Univ.)

Chris Wikle (Univ. Missouri)

Tommy Wright (U.S. Census Bureau)

Despite the inclusion of highly accomplished and distinguished statisticians on the Task Force, there were isolated demurrers. Geoff Cumming, for one, clucked:

“Why won’t statistical significance simply whither and die, taking p <. 05 and maybe even p-values with it? The ASA needs a Task Force on Statistical Inference and Open Science, not one that has its eye firmly in the rear view mirror, gazing back at .05 and significance and other such relics.”[9]

Despite the clucking, the Taskforce arrived at its recommendations, but curiously, its report did not find a home in an ASA publication. Instead, the “The ASA President’s Task Force Statement on Statistical Significance and Replicability” has now appeared as an “in press” publication at The Annals of Applied Statistics, where Karen Kafadar is the editor in chief.[10] The report is accompanied by an editorial by Kafadar.[11]

The Taskforce advanced five basic propositions, which may have been obscured by some of the recent glosses on the ASA 2016 p-value statement:

  1. “Capturing the uncertainty associated with statistical summaries is critical.”
  2. “Dealing with replicability and uncertainty lies at the heart of statistical science. Study results are replicable if they can be verified in further studies with new data.”
  3. “The theoretical basis of statistical science offers several general strategies for dealing with uncertainty.”
  4. “Thresholds are helpful when actions are required.”
  5. “P-values and significance tests, when properly applied and interpreted, increase the rigor of the conclusions drawn from data.”

All of this seems obvious and anodyne, but I suspect it will not silence the clucking.


[1] Deborah Mayo, “Alas! The ASA President’s Task Force Statement on Statistical Significance and Replicability,” Error Statistics (June 20, 2021).

[2]Falsehood Flies – The ASA 2016 Statement on Statistical Significance” (Feb. 26, 2021).

[3] Ronald L. Wasserstein & Nicole A. Lazar, “The ASA’s Statement on p-Values: Context, Process, and Purpose,” 70 The Am. Statistician 129 (2016); see “The American Statistical Association’s Statement on and of Significance” (March 17, 2016).

[4]The American Statistical Association Statement on Significance Testing Goes to Court – Part I” (Nov. 13, 2018); “The American Statistical Association Statement on Significance Testing Goes to Court – Part 2” (Mar. 7, 2019).

[5]Has the American Statistical Association Gone Post-Modern?” (Mar. 24, 2019); “American Statistical Association – Consensus versus Personal Opinion” (Dec. 13, 2019). See also Deborah G. Mayo, “The 2019 ASA Guide to P-values and Statistical Significance: Don’t Say What You Don’t Mean,” Error Statistics Philosophy (June 17, 2019); B. Haig, “The ASA’s 2019 update on P-values and significance,” Error Statistics Philosophy  (July 12, 2019); Brian Tarran, “THE S WORD … and what to do about it,” Significance (Aug. 2019); Donald Macnaughton, “Who Said What,” Significance 47 (Oct. 2019).

[6] Ronald L. Wasserstein, Allen L. Schirm, and Nicole A. Lazar, “Editorial: Moving to a World Beyond ‘p < 0.05’,” 73 Am. Statistician S1, S2 (2019).

[7] Karen Kafadar, “The Year in Review … And More to Come,” AmStat News 3 (Dec. 2019) (emphasis added); see Kafadar, “Statistics & Unintended Consequences,” AmStat News 3,4 (June 2019).

[8] Karen Kafadar, “Task Force on Statistical Significance and Replicability,” ASA Amstat Blog (Feb. 1, 2020).

[9] See, e.g., Geoff Cumming, “The ASA and p Values: Here We Go Again,” The New Statistics (Mar. 13, 2020).

[10] Yoav Benjamini, Richard D. DeVeaux, Bradly Efron, Scott Evans, Mark Glickman, Barry Braubard, Xuming He, Xiao Li Meng, Nancy Reid, Stephen M. Stigler, Stephen B. Vardeman, Christopher K. Wikle, Tommy Wright, Linda J. Young, and Karen Kafadar, “The ASA President’s Task Force Statement on Statistical Significance and Replicability,” 15 Annals of Applied Statistics 2021, available at https://www.e-publications.org/ims/submission/AOAS/user/submissionFile/51526?confirm=79a17040.

[11] Karen Kafadar, “Editorial: Statistical Significance, P-Values, and Replicability,” 15 Annals of Applied Statistics 2021, available at https://www.e-publications.org/ims/submission/AOAS/user/submissionFile/51525?confirm=3079934e.

Judge Jack B. Weinstein – A Remembrance

June 17th, 2021

There is one less force of nature in the universe. Judge Jack Bertrand Weinstein died earlier this week, about two months shy of a century.[1] His passing has been noticed by the media, lawyers, and legal scholars[2]. In its obituary, the New York Times noted that Weinstein was known for his “bold jurisprudence and his outsize personality,” and that he was “revered, feared, and disparaged.” The obituary quoted Professor Peter H. Schuck, who observed that Weinstein was “something of a benevolent despot.”

As an advocate, I found Judge Weinstein to be anything but fearsome. His jurisprudence was often driven by intellectual humility rather than boldness or despotism. One area in which Judge Weinstein was diffident and restrained was in his exercise of gatekeeping of expert witness opinion. He, and his friend, the late Professor Margaret Berger, were opponents of giving trial judges discretion to exclude expert witness opinions on ground of validity and reliability. Their antagonism to gatekeeping was, no doubt, partly due to their sympathies for injured plaintiffs and their realization that plaintiffs’ expert witnesses often come up with dodgy scientific opinions to advance plaintiffs’ claims. In part, however, Judge Weinstein’s antagonism was due to his skepticism about judicial competence and his own intellectual humility.

Although epistemically humble, Judge Weinstein was not incurious. His interest in scientific issues occasionally got him into trouble, as when he was beguiled by Dr. Irving Selikoff and colleagues, who misled him on aspects of the occupational medicine of asbestos exposure. In 1990, Judge Weinstein issued a curious mea culpa. Because of a trial in progress, Judge Weinstein, along with state judge (Justice Helen Freedman), attended an ex parte private luncheon meeting with Dr. Selikoff. Here is how Judge Weinstein described the event:

“But what I did may have been even worse [than Judge Kelly’s conduct that led to his disqualification]. A state judge and I were attempting to settle large numbers of asbestos cases. We had a private meeting with Dr. Irwin [sic] J. Selikoff at his hospital office to discuss the nature of his research. He had never testified and would never testify. Nevertheless, I now think that it was a mistake not to have informed all counsel in advance and, perhaps, to have had a court reporter present and to have put that meeting on the record.”[3]

Judge Weinstein’s point about Selikoff’s having never testified was demonstrably false, but I impute no scienter for false statements to the judge. The misrepresentation almost certainly originated with Selikoff. Dr. Selikoff had testified frequently up to the point at which he and plaintiffs’ counsel realized that his shaky credentials and his pronouncements on “state of the art,” were hurtful to the plaintiffs’ cause. Even if Selikoff had not been an accomplished testifier, any disinterested observer should, by 1990, have known that Selikoff was himself not a disinterested actor in medical asbestos controversies.[4] The meeting with Selikoff apparently weighed on Judge Weinstein’s conscience. He repeated his mea culpa almost verbatim, along with the false statement about Selikoff’s never having testified, in a law review article in 1994, and then incorporated the misrepresentation into a full-length book.[5]

In his famous handling of the Agent Orange class action, Judge Weinstein manipulated the defendants into settling, and only then applied his considerable analytical ability in dissecting the inadequacies of the plaintiffs’ causation case. Rather than place the weight of his decision on Rule 702, Judge Weinstein dismembered the causation claim by finding that the bulk of what the plaintiffs’ expert witnesses relied upon under Rule 703 was unreasonable. He then found that what remained, if anything, could not reasonably support a verdict for plaintiffs, and he entered summary judgment for the defense in the opt-out cases.[6]

In 1993, the U.S. Supreme Court breathed fresh life into the trial court’s power and obligation to review expert witness opinions and to exclude unsound opinions.[7] Several months before the Supreme Court charted this new direction on expert witness testimony, the silicone breast implant litigation, fueled by iffy science and iffier scientists, erupted.[8] In October 1994, the Judicial Panel on Multi-District Litigation created MDL 926, which consolidated the federal breast implant cases before Judge Sam Pointer, in the Northern District of Alabama. Unlike most contemporary MDL judges, however, Judge Pointer did not believe that Rule 702 and 703 objections should be addressed by the MDL judge. Pointer believed strongly that the trial judges, in the individual, remanded cases, should rule on objections to the validity of proffered expert witness opinion testimony. As a result, so-called Daubert hearings began taking place in district courts around the country, in parallel with other centralized proceedings in MDL 926.

By the summer of 1996, Judge Robert E. Jones had a full-blown Rule 702 attack on the plaintiffs’ expert witnesses before him, in a case remanded from MDL 926. In the face of the plaintiffs’ MDL leadership committee’s determined opposition, Judge Jones appointed four independent scientists to serve as scientific advisors. With their help, in December 1996, Judge Jones issued one of the seminal rulings in the breast implant litigation, and excluded the plaintiffs’ expert witnesses.[9]

While Judge Jones was studying the record, and writing his opinion in the Hall case, Judge Weinstein, with a judge from the Southern District of New York, conducted a two-week Rule 702 hearing, in his Brooklyn courtroom. Judge Weinstein announced at the outset that he had studied the record from the Hall case, and that he would incorporate it into his record for the cases remanded to the Southern and Eastern Districts of New York.

I had one of the first witnesses, Dr. Donnard Dwyer, before Judge Weinstein during that chilly autumn of 1996. Dwyer was a very earnest immunologist, who appeared on direct examination to endorse the methodological findings of the plaintiffs’ expert witnesses, including a very dodgy study by Dr. Douglas Shanklin. On cross-examination, I elicited Dwyer’s view that the Shanklin study involved fraudulent methodology and that he, Dwyer, would never use such a method or allow a graduate student to use it. This examination, of course, was great fun, and as I dug deeper with relish, Judge Weinstein stopped me, and asked rhetorically to the plaintiffs’ counsel, whether any of them intended to rely upon the discredited Shanklin study. My main adversary Mike Williams did not miss a beat; he jumped to his feet to say no, and that he did not know why I was belaboring this study. But then Denise Dunleavy, of Weitz & Luxenberg, knowing that Shanklin was her listed expert witness in many cases, rose to say that her expert witnesses would rely upon the Shanklin study. Incredulous, Weinstein looked at me, rolled his eyes, paused dramatically, and then waved his hand at me to continue.

Later in my cross-examination, I was inquiring about another study that reported a statistic from a small sample. The authors reported a confidence interval that included negative values for a test that could not have had any result less than zero. The sample was obviously skewed, and the authors had probably used an inappropriate parametric test, but Dwyer was about to commit to the invalidity of the study when Judge Weinstein stopped me. He was well aware that the normal approximation had created the aberrant result, and that perhaps the authors only sin was in failing to use a non-parametric test. I have not had many trial judges interfere so knowledgably.

In short order, on October 23, 1996, Judge Weinstein issued a short, published opinion, in which he ducked the pending Rule 702 motions, and he granted partial summary judgment on the claims of systemic disease.[10] Only the lawyers involved in the matters would have known that there was no pending motion for summary judgment!

Following up with grant of summary judgment, Judge Weinstein appointed a group of scientists and a legal scholar, to help him assemble a panel of Rule 706 expert witnesses for future remanded case. Law Professor Margaret Berger, along with Drs. Joel Cohen and Alan Wolff, began meeting with the lawyers to identify areas of expertise needed by the court, and what the process of court-appointment of neutral expert witnesses would look like.

The plaintiffs’ counsel were apoplectic. They argued to Judge Weinstein that Judge Pointer, in the MDL, should be supervising the process of assembling court-appointed experts. Of course, the plaintiffs’ lawyers knew that Judge Pointer, unlike Judges Jones and Weinstein, believed that both sides’ expert witnesses were extreme, and mistakenly believed that the truth lay between. Judge Pointer was an even bigger foe of gatekeeping, and he was generally blind to the invalid evidence put forward by plaintiffs. In response to the plaintiffs’ counsel’s, Judge Weinstein sardonically observed that if there were a real MDL judge, he should take it over.

Within a month or so, Judge Pointer did, in fact, take over the court-appointed expert witness process, and incorporated Judge Weinstein’s selection panel. The process did not going very smoothly in front of the MDL judge, who allowed the plaintiffs lawyers to slow down the process by throwing in irrelevant documents and deploying rhetorical tricks. The court-appointed expert witnesses did not take kindly to the shenanigans, or to the bogus evidence. The expert panel’s unanimous rejection of the plaintiffs’ claims of connective tissue disease causation was an expensive, but long overdue judgment from which there was no appeal. Not many commentators, however, know that the panel would never have happened but for Judge Weinstein’s clever judicial politics.

In April 1997, while Judge Pointer was getting started with the neutral expert selection panel,[11] the parties met with Judge Weinstein one last time to argue the defense motions to exclude the plaintiffs’ expert witnesses. Invoking the pendency of the Rule 706 court-appointed expert witness processs in the MDL, Judge Weinstein quickly made his view clear that he would not rule on the motions. His Honor also made clear that if we pressed for a ruling, he would deny our motions, even though he had also ruled that plaintiffs’ could not make out a submissible case on causation.

I recall still the frustration that we, the defense counsel, felt that April day, when Judge Weinstein tried to explain why he would grant partial summary judgment but not rule on our motions contra plaintiffs’ expert witnesses. It would be many years later, before he let his judicial assessment see the light of day. Two decades and then some later, in a law review article, Judge Weinstein made clear that “[t]he breast implant litigation was largely based on a litigation fraud. …  Claims—supported by medical charlatans—that enormous damages to women’s systems resulted could not be supported.”[12] Indeed.

Judge Weinstein was incredibly smart and diligent, but he was human with human biases and human fallibilities. If he was a despot, he was at least kind and benevolent. In my experience, he was always polite to counsel and accommodating. Appearing before Judge Weinstein was a pleasure and an education.


[1] Laura Mansnerus, “Jack B. Weinstein, U.S. Judge With an Activist Streak, Is Dead at 99,” N.Y. Times (June 15, 2021).

[2] Christopher J. Robinette, “Judge Jack Weinstein 1921-2021,” TortsProf Blog (June 15, 2021).

[3] Jack B. Weinstein, “Learning, Speaking, and Acting: What Are the Limits for Judges?” 77 Judicature 322, 326 (May-June 1994).

[4]Selikoff Timeline & Asbestos Litigation History” (Dec. 20, 2018).

[5] See Jack B. Weinstein, “Limits on Judges’ Learning, Speaking and Acting – Part I- Tentative First Thoughts: How May Judges Learn?” 36 Ariz. L. Rev. 539, 560 (1994) (“He [Selikoff] had never testified and would never testify.”); Jack B. Weinstein, Individual Justice in Mass Tort Litigation: The Effect of Class Actions, Consolidations, and other Multi-Party Devices 117 (1995) (“A court should not coerce independent eminent scientists, such as the late Dr. Irving Selikoff, to testify if, like he, they prefer to publish their results only in scientific journals.”)

[6] In re Agent Orange Product Liab. Litig., 597 F. Supp. 740, 785 (E.D.N.Y. 1984), aff’d 818 F.2d 145, 150-51 (2d Cir. 1987)(approving district court’s analysis), cert. denied sub nom. Pinkney v. Dow Chemical Co., 487 U.S. 1234 (1988);  In re “Agent Orange” Prod. Liab. Litig., 611 F. Supp. 1223 (E.D.N.Y. 1985), aff’d, 818 F.2d 187 (2d Cir. 1987), cert. denied, 487 U.S. 1234 (1988).

[7] Daubert v. Merrell Dow Pharmaceuticals, Inc., 509 U.S. 579 (1993).

[8] Reuters, “Record $25 Million Awarded In Silicone-Gel Implants Case,” N.Y. Times (Dec. 24, 1992).

[9] See Hall v. Baxter Healthcare Corp., 947 F. Supp. 1387 (D. Ore. 1996).

[10] In re Breast Implant Cases, 942 F. Supp. 958 (E.& S.D.N.Y. 1996).

[11] MDL 926 Order 31 (May 31, 1996) (order to show cause why a national Science Panel should not be appointed under Federal Rule of Evidence 706); MDL 926 Order No. 31C (Aug. 23, 1996) (appointing Drs. Barbara S. Hulka, Peter Tugwell, and Betty A. Diamond); Order No. 31D (Sept. 17, 1996) (appointing Dr. Nancy I. Kerkvliet).

[12] Hon. Jack B. Weinstein, “Preliminary Reflections on Administration of Complex Litigation” 2009 Cardozo L. Rev. de novo 1, 14 (2009) (emphasis added).

Scientists Suing Scientists, and Behaving Badly

June 2nd, 2021

In his 1994 Nobel Prize acceptance speech, the Hungarian born chemist George Andrew Olah acknowledged an aspect of science that rarely is noted in popular discussions:

“[One] way of dealing with errors is to have friends who are willing to spend the time necessary to carry out a critical examination of the experimental design beforehand and the results after the experiments have been completed. An even better way is to have an enemy. An enemy is willing to devote a vast amount of time and brain power to ferreting out errors both large and small, and this without any compensation. The trouble is that really capable enemies are scarce; most of them are only ordinary. Another trouble with enemies is that they sometimes develop into friends and lose a good deal of their zeal. It was in this way the writer lost his three best enemies. Everyone, not just scientists, need a few good enemies!”[1]

If you take science seriously, you must take error as something for which we should always be vigilant, and something we are committed to eliminate. As Olah and Von Békésy have acknowledged, sometimes an enemy is required. It would thus seem to be quite unscientific to complain that an enemy was harassing you, when she was criticizing your data, study design, methods, or motives.

Elisabeth Margaretha Harbers-Bik would be a good enemy to have. Trained in the Netherlands in microbiology, Dr. Bik came to the United States, where for some years she conducted research at Stanford University. In 2018, Bik began in earnest a new career in analyzing published scientific studies for image duplication and manipulation, and other dubious practices.[2]

Her blog, Scientific Integrity Digest, should be on the reading list of every lawyer who labors in the muck of science repurposed for litigation. You never know when your adversary’s expert witness will be featured in the pages of the Digest!

Dr. Bik is not a lone ranger; there are other scientists who have committed to cleaning up the scientific literature. After an illustrious career as an editor of prestigious journals, and a director of the Rockefeller University Press, Dr. Mike Rossner founded Image Data Integrity, Inc., to stamp out image fraud and error in scientific publications.

On March 16, 2020, a gaggle of French authors, including Dr. Didier Raoult, uploaded a pre-print of a paper to medRxiv, reporting on hydroxychloroquine (HCQ) and azithromycin in Covid-19 patients. The authors submitted their manuscript that same day to the International Journal of Antimicrobial Agents, which accepted it in 24 hours or less, on March 17, 2020. The journal published the paper online, three days after acceptance, on March 20th. Peer-review, to the extent it took place, was abridged.[3]

The misleading title of the paper, “Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial,” may have led some untutored observers into thinking the paper reported a study high in the hierachy of evidence. Instead the paper was a rather flawed observational study, or perhaps just a concatenation of anecdotes. In any event, the authors reported that patients who had received both medications cleared the SARS-CoV2 the fastest.

Four days after publication online at a supposedly peer-reviewed journal, Elisabeth Bik posted an insightful analysis of the Raoult paper.[4] If peer review it were, her blog post pointed out the review’s failure by identifying an apparent conflict of interest and various methodological flaws, including missing data on six (out of 26) patients, including one patient who died, and three whose conditions worsened on therapy.

Raoult’s paper, and his overly zealous advocacy for HCQ did not go unnoticed in the world of kooks, speculators, and fraudfeasors. Elon Musk tweeted about Raoult’s paper; and Fox News amplified Musk’s tweet, which made it into the swamp of misinformation, Trump’s mind and his twitterverse.[5]

In the wake of the hoopla over Raoult’s paper, the journal owner admitted that the paper did not live up to the society’s standards. The publisher, Elsevier, called for an independent investigation. The French Infectious Diseases Society accused Raoult of spreading false information about hydroxychloroquine’s efficacy in Covid-19 patients. To date, there has been no further official discussions of disciplinary actions or proceedings at the Society.

Raoult apparently stewed over Bik’s criticisms and debunking of his over-interpretation of his flawed HCQ study.  Last month, Raoult filed a complaint with a French prosecutor, which marked the commencement of legal proceedings against Bik for harassment and “extortion.” The extortion charge is based upon nothing more than Bik’s having a Patreon account to support her search for fraud and error in the published medical literature.[6]

The initial expression of outrage over Marseille Raoult’s bad behavior came from Citizen4Science, a French not-for-profit organization that works to promote scientific integrity. According to Dr. Fabienne Blum, president of Citizen4Science, the organization issued its press release on May 5, 2021, to call on authorities to investigate and to intervene in Raoult’s harassment of scientists. Their press release about “the French scandal” was signed by scientists and non-scientists from around the world; it currently remains open for signatures, which number well over 4,000. “Harassment of scientific spokespersons and defenders of scientific integrity: Citizen4Science calls on the authorities to intervene urgently” (May 5, 2021). Dr. Blum and Citizen4Science are now harassed on Twitter, where they have been labeled “Bik’s gang.” Inevitably, they will be sued as well.

On June 1st, Dr. Raoult posted his self-serving take on the controversy on that scholarly forum known as YouTube. An English translation of Raoult’s diatribe can be found at Citizen4Science’s website. Perhaps others have noted that Raoult refers to Bik as “Madame” (or Mrs.) Bik, rather than as Dr. Bik, which leads to some speculation that Raoult has trouble taking criticism from intelligent women.

Having projected his worst characteristics onto adversaries, Raoult lodged accusations against Bik, which actually reflected his own behaviors closely. Haven’t we seen someone in public life who operates just like this? Raoult has criticized Bik in the lay media, and he released personal information about her, including her residential address. Raoult’s intemperate and inappropriate personal attacks on Bik have led several hundred scientists to sign an open letter in support of Bik.[7]

This scientist doth protest too much, methinks.


[1] George Andrew Olah Nobel Prize Speech (1994) (quoting from George Von Békésy, Experiments in Hearing 8 (1960).

[2] Elisabeth M. Bik, Arturo Casadevall, and Ferric C. Fang, “The Prevalence of Inappropriate Image Duplication in Biomedical Research Publications,” 7 mBio e00809 (2016); Daniele Fanelli, Rodrigo Costas, Ferric C. Fang, Arturo Casadevall, Elisabeth M. Bik, “Testing Hypotheses on Risk Factors for Scientific Misconduct via Matched-Control Analysis of Papers Containing Problematic Image Duplications,” 25 Science & Engineering Ethics 771 (2019); see also Jayashree Rajagopalan, “I have found about 2,000 problematic papers, says Dr. Elisabeth Bik,” Editage Insights (Aug 08, 2019).

[3] Philippe Gautret, Jean-Christophe Lagier, Philippe Parola, Van Thuan Hoang, Line Meddeb, Morgane Mailhe, Barbara Doudier, Johan Courjon, Valérie Giordanengo, Vera Esteves Vieira, Hervé Tissot Dupont, Stéphane Honoré, Philippe Colson, Eric Chabrière, Bernard La Scola, Jean-Marc Rolain, Philippe Brouqui, and Didier Raoult, “Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial,” 56 Clinical Trial Internat’l J. Antimicrob. Agents e105949 (2020).

[4] Bik, “Thoughts on the Gautret et al. paper about Hydroxychloroquine and Azithromycin treatment of COVID-19 infections,” Scientific Integrity Digest (March 24, 2020).

[5] Charles Piller, “‘This is insane!’ Many scientists lament Trump’s embrace of risky malaria drugs for coronavirus,” Science Mag. (Mar. 26, 2020).

[6] Melissa Davey, “World expert in scientific misconduct faces legal action for challenging integrity of hydroxychloroquine study,” The Guardian (May 22, 2021); Kristina Fiore, “HCQ Doc Sues Critic,” MedPage Today (May 26, 2021).

[7] Lonni Besançon, Alexander Samuel, Thibault Sana, Mathieu Rebeaud, Anthony Guihur, Marc Robinson-Rechavi, Nicolas Le Berre, Matthieu Mulot, Gideon Meyerowitz-Katz, Maisonneuve, Brian A. Nosek, “Open Letter: Scientists stand up to protect academic whistleblowers and post-publication peer review,” (May 18, 2021).